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DMH1 by itself did not induce cell Dying in MCF-seven and HeLa cells, but inhibited the proliferation of those cells. In summary, DMH1 inhibits chemotherapeutic drug-induced autophagy reaction and the enhancement of efficacy of chemotherapeutic medicine by DMH1 is depending on the cell sensitivity to medicine. See publication DMH1, a small molecule

Summary Indeed-involved protein one (YAP1) and its paralogue PDZ-binding motif (TAZ) Enjoy pivotal roles in cell proliferation, migration, and invasion, and abnormal activation of such TEAD transcriptional coactivators is found in diverse cancers in individuals and mice. Concentrating on YAP1/TAZ signaling is Therefore a promising therapeutic avenu